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N-Ethyl-nor-pentedrone (also known as N-Ethylpentedrone, Ethyl-pentedrone or more commonly, NEP) is a lesser-known novel stimulant substance of the cathinone class that produces stimulating, euphoric, and mildly entactogenic effects when administered. The stimulating effects of NEP are believed to mainly be caused by its activity as a norepinephrine-dopamine reuptake inhibitor (NDRI). The reported entactogenic effects it displays may also be due to its activity as a serotonin reuptake inhibitor or releasing agent in moderate to high doses, although new research has shown very low serotonin reuptake inhibition. NEP acts as unselective serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).

NEP shares a close structural relationship to its parent compound Pentedrone, differing by an addition ethyl group on the terminal nitrogen on the carbon chain. This addition reportedly makes it about three times as potent as pentedrone. NEP is also closely related to N-Ethylhexedrone (Hexen), and has been reported as producing largely-similar effects.

AN USER EXPERIENCE ABOUT NEP:
"... I am feeling energetic, confident and happy now, the effects are very noticeable but not overwhelming. All in all I think it's a great substance, I hope soon more info will come out about the health effects of it. It honestly feels better than coke, the only thing that's not as nice is the taste and drip. The lovely numbness my nose gets from coke is also missing. ... "

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How to Buy NEP

You can buy NEP and other research chemicals here at LIZARD-LAB. All of our chemicals are third party lab tested. If you wish to see HNMR results for NEP or any other chemical, just email us at

Responsible Research with NEP

Always practice responsible research. You should read and educate yourself before undertaking research with any chemical. The Psychonaut Wiki has some very helpful resources and information on NEP , so does The Third Wave. Never conduct research with a chemical without learning about it first.

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NEP and all other products are strictly for research purposes only and not for human consumption.

Store NEP in a cool, dry place away from sunlight.

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NEP stock last updated at: April 2025

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